POLYNUCLEOTIDES: THE UNDER-EYE TREATMENT THAT STRENGTHENS SKIN FROM WITHIN
Why I use them for regeneration, resilience and natural rejuvenation.
In recent years, the approach to aesthetic treatments has shifted more and more towards improving skin health rather than simply adding volume. Patients don’t just want to look different — they want to look fresher, healthier, and more like themselves.
IMPROVE YOUR SKIN.
Polynucleotides are particularly effective around the delicate eye area, where skin is thin and ageing changes show early. But I also use them more widely as a skin preparation treatment, helping to strengthen and repair tissue before other procedures or simply to improve long-term skin quality.
At Moreton Aesthetics, they form part of my regenerative treatment plans because they work with your biology rather than against it.
What Are Polynucleotides?
Polynucleotides are injectable molecules derived from purified DNA fragments. They don’t act like dermal filler and they don’t create volume. Instead, they stimulate your skin to repair itself at a cellular level.
They support multiple regenerative processes, including:
Collagen production
Elastin formation
Tissue repair and regeneration
Hydration improvement
Anti-inflammatory activity
Skin barrier strengthening
I often describe them to patients as skin quality therapy — they help skin behave more like younger, healthier tissue again.
Why They’re Especially Powerful for the Eye Area
The under-eye region is one of the most challenging areas to treat because:
The skin is extremely thin
Collagen declines early
Blood vessels show through easily
Fine lines develop quickly
Elasticity reduces with age
Many patients assume filler is the only solution, but that isn’t always true — and sometimes filler isn’t appropriate at all.
Polynucleotides are particularly effective here because they can:
Thicken fragile under-eye skin
Improve elasticity and firmness
Reduce crepey texture
Enhance hydration
Support microcirculation
Brighten overall appearance
The result is usually a fresher, healthier-looking eye area rather than an obvious cosmetic change.
My Philosophy: Strengthen Before You Fill
One of the ways I most value polynucleotides is as a preparation treatment.
When skin is stronger, it responds better to almost everything else we do.
Improved skin quality can enhance outcomes from:
It’s similar to preparing foundations before building — the stronger the base, the better the result.
Who I Recommend Polynucleotides For
In my clinic, I suggest this treatment for patients who notice:
Tired or ageing under-eyes
Fine lines or crepey texture
Skin thinning with age
Early laxity
Poor skin resilience
Dull or dehydrated skin
Preventative ageing goals
They are suitable for a wide range of ages, from younger patients wanting prevention to more mature patients needing regeneration.
Polynucleotides vs Dermal Filler
Patients often ask which is better.
The truth is they do completely different things.
Dermal filler restores structure and replaces lost volume.
Polynucleotides improve skin quality and tissue health.
Sometimes one treatment is enough. Sometimes combining them gives the most natural result.
The decision depends entirely on anatomy and goals, which is why personalised assessment is essential.
What Treatment Is Like
Treatment involves a series of very small injections placed into the skin, either with a needle or cannula . Most patients tolerate it well, and I use techniques to keep the procedure comfortable.
Afterwards, you may notice:
Mild swelling
Small bumps at injection points
Slight redness or bruising
These effects usually settle within a few days, particularly around the eyes where the skin is delicate.
Downtime is generally minimal.
How Many Sessions Are Needed?
Polynucleotides work cumulatively because they stimulate regeneration rather than creating instant change.
I usually recommend:
Three+ sessions
Spaced about 2–4 weeks apart
Maintenance treatments every 6–12 months help sustain results depending on your skin and goals.
Improvement continues gradually as collagen develops over time.
What Results I See Clinically
Patients often notice:
Smoother under-eye skin
Improved elasticity
Reduced crepey appearance
Better hydration
Brighter, fresher look
Improved makeup application
Healthier overall skin quality
The change is subtle but meaningful — people tend to look well-rested rather than treated.
Why I Value This Treatment
As a clinician, I’m always looking for treatments that support long-term skin health rather than short-term cosmetic fixes.
Polynucleotides fit beautifully into this philosophy because they:
Work with your natural biology
Strengthen tissue over time
Improve resilience
Enhance other treatments
Produce natural-looking results
They are particularly helpful for patients who want improvement without adding volume, or who are not yet ready for filler.
The Takeaway
Polynucleotides are one of the most versatile regenerative treatments available today.
They are especially beneficial for:
Under-eye rejuvenation
Skin strengthening
Preventative ageing
Treatment preparation
Natural skin improvement
Healthy skin ages better — and this treatment helps support that process.
Considering Polynucleotides?
If you’re concerned about under-eye ageing or want to strengthen your skin before other treatments, a consultation will help determine whether polynucleotides are right for you.
Sometimes improving skin quality is the most important step in any aesthetic journey.
I’m not just your aesthetic practitioner; I’m here to connect with you. Have questions or eager to discuss your skincare journey? Reach out to me. Your queries and thoughts are always welcome.
YOUR NEXT STEPS
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Book Your Consultation – Ready to take the plunge? Book a consultation to meet me and begin your journey to radiant skin.
See My Before & Afters – Head over to Glowday to witness skin transformations.
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Thank you for considering Moreton Aesthetics for your facial aesthetics journey. I look forward to welcoming you on your transformative adventure.
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